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KMID : 0605720120180020281
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Journal of the Korean Society of Biological Therapies in Psychiatry
2012 Volume.18 No. 2 p.281 ~ p.289
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Prevalence of Metabolic Syndrome in Chronic Schizophrenic Inpatients
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Kang Kam-Doo
Shee Young-Hwa
Yoon Bo-Hyun
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Abstract
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Objectives: The purpose of this study was to evaluate the prevalence and characteristics of metabolic syndrome in Korean schizophrenic inpatients in a national mental hospital.
Methods: Schizophrenic inpatients who met the diagnosis of DSM-IV-TR were included. Body weight, height, waist circumference and blood pressure were directly checked by the authors. Data on blood glucose, triglyceride, HDL-cholesterol were gathered from the fasting state blood samples before breakfast. Metabolic syndrome was defined by revised National Cholesterol Education Program-Adult Treatment Panel III(revised NCEP-ATP-III) and criteria of International Diabetes Federation(IDF).
Results: A total of 213 inpatients were included. 104(48.8%) and 95(44.6%) of them were diagnosed as metabolic syndrome by criteria of revised NCEP-ATP III and IDF, respectively. Of the 5 cardiometabolic risks, abdominal obesity and impaired glucose level were significantly more common in women. The frequencies of the cardiometabolic risks were as follows; abdominal obesity(67.1%), low HDL-cholesterol(50.7%), triglyceridemia(47.9%), impaired blood glucose level(44.1%) and hypertension(27.2%). Although the correlation of metabolic syndrome with sex was significant, current age, age at onset, duration of illnesses, and numbers of prescribed antipsychotic were not significantly correlated. Logistic regression revealed that female sex(OR=2.27) and low economic status(OR=1.99) were significant predictors of metabolic syndrome in schizophrenic inpatients by IDF criteria.
Conclusions: Our results suggest that the prevalence of metabolic syndrome in schizophrenic inpatients may be twice than that of general population in Korea. Female sex and low economic status were significant predictors of metabolic syndrome in schizophrenic inpatients.
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KEYWORD
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Metabolic syndrome, Schizophrenic Inpatients, Prevalence, NCEP-ATP III, IDF
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